Joshua Wesalo, MD, PhD

Education & Training

  • Franklin & Marshall College, BA, 2013
  • University of Pittsburgh, PhD, 2021
  • University of Pittsburgh, MD, 2023

Representative Publications

Brown, W., Wesalo, J., Samanta, S., Luo, J., Caldwell, S. E., Tsang, M., & Deiters, A. (2023). Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein–Nucleotide Interactions in Zebrafish Embryos. ACS Chemical Biology.

[submitted manuscript] Joest, E. F.; Winter, C.; Wesalo, J. S.; Deiters, A.; Tampé, R. “Efficient Amber Suppression by Ribosomal Skipping for In Situ Synthesis of Photoconditional Nanobodies.” Angewandte Chemie.

Joest, E. F.; Winter, C.; Wesalo, J. S.; Deiters, A.; Tampé, R. “Light-guided intrabodies for on-demand in situ target recognition in human cells.” Chem. Sci. 2021, 12, 5787–5795.

Zhou, W.; Wesalo, J. S.; Liu, J.; Deiters, A. “Genetic code expansion in mammalian cells: A plasmid system comparison.” Bioorg. Med. Chem. 2020, 28, 115772.

Wesalo, J. S.; Deiters, A. “Fast phosphine-activated control of protein function using unnatural lysine analogues.” Methods Enzymol. 2020, 638, 191–217.

Wesalo, J. S.; Luo, J.; Morihiro, K.; Liu, J.; Deiters, A. “Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation.” ChemBioChem 2020, 21, 141–148

Career Advisor

Donald DeFranco, PhD

Thesis Advisor

Alex Deiters, PhD

Graduate Program

Dissertation Title

Optical and small-molecule control of protein and nucleic acid function

graduate year

2023

Trainee

Past

Training Period

2014 - 2023